Gas Chromatography (GC): Gas Chromatography is used for analysis of mixtures of volatile and semi-volatile organic compounds (VOC's and SVOC's). GC with flame ionization detection (FID) is commonly used for quantitative analysis of known target compounds.
Gas Chromatography-Mass Spectrometry (GC-MS): GC-MS is a powerful technique that can provide identification of unknowns in complex mixtures. GC-MS is a great technique for analysis of trace level impurities such as residual monomers because of its excellent sensitivity and specificity.
Headspace Gas Chromatography: Headspace GC or GC-MS can be used to test for volatile organic compounds (VOC's) such as residual solvents in solid or liquid samples.
High-Performance Liquid Chromatography (HPLC): Reverse-phase HPLC is used for testing of non-polar compounds such as polymer antioxidants and UV absorbers. Normal phase HPLC and HILIC are also used depending on the polarity of the compounds of interest.
Liquid Chromatography Mass Spectrometry (LC-MS): LC-MS combines the separation ability of HPLC with the identification capability of mass spectrometry. LC-MS is useful for reformulation or extractable/leachable analysis of samples that may contain non-volatile additives or impurities.
Size Exclusion Chromatography (SEC): Also known as Gel Permeation Chromatography (GPC), SEC is used to measure the molecular weight distribution of a polymer sample. The molecular weight measurement may be performed using multi-angle light scattering (MALS) to obtain the absolute molecular weight.
Lactic acid and glycolic acid polymers (PLLA and PLGA) used in restorable medical implants, drug-eluting stents, and nanoparticles. Polyesters, polyamides, polyurethanes, polyolefins, and silicone polymers used in medical packaging, tubing, and catheters.
Pharmaceutical packaging and delivery systems. Controlled release formulations. Pharmaceutical actives, intermediates, raw materials, and combination devices.